The D6#105

The D6 is an unlockable activated item.

• Although the D6 is considered a Special Item, it will only count as a special item if found naturally during gameplay. Starting with the D6 as Isaac will not cause fewer special items to appear later on. This fact also extends to Eden's starting items: if Eden starts with a special item, that item will not count toward the special item total.
• In the original Binding of Isaac, the D6 had a recharge time of 3 instead of 6.
• The D6 could not reroll special boss items in the original game, such as Little C.H.A.D. and Little Steven.
• In the Eternal Edition of the original Binding of Isaac, The D6 has a chance to delete the item instead of rerolling it when playing in hard mode.
• The Eternal D6 has the same effect but with a 2 room charge.
• In the original Binding of Isaac, this item was called "The Dice".
• Like the other dice items, the D6 uses the naming scheme of dice for tabletop RPGs like Dungeons & Dragons, which were associated with devil worship during the Satanic Panic.
• The D7, D8, D12, D20, D100, Spindown Dice, and D infinity has the sides displayed with numbers, while D1, D4, The D6, and the Eternal D6 has sides displayed with pips.
• The D6 is the only dice item that includes ‘The’ in its name.
• This may be because it is ‘The’ quintessential dice item; being the first added to the game, arguably the most iconic, and the only one featured as a starting item - for Isaac himself, no less.