???'s Only Friend#320

???'s Only Friend is an unlockable passive item.

• The sprite for the familiar resembles a Boom Fly, which has been resprited to fit the blue/dead nature of ??? and Hush, similar to the Hush Fly, Blue Gaper, and Fate's Reward
• This item is slightly faster than Robo-Baby 2.0, but is only noticeable when rapid clicking the tear button. Fly Items Items
• ???'s Only Friend
• Angry Fly
• BBF
• Best Bud
• Big Fan
• Bot Fly
• Brown Nugget
• Distant Admiration
• Forever alone
• Friend Zone
• Fruity Plum
• Halo of Flies
• Hive Mind
• Infestation
• Jar of Flies
• Lost Fly
• The Mulligan
• Obsessed Fan
• Papa Fly
• Psy Fly
• Skatole
• Smart Fly
• The Swarm ??? (Character) Unlocks Boss Rush Unlocks The Binding of Isaac: Rebirth
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