Vade Retro#653

Vade Retro is an unlockable activated item added in The Binding of Isaac: Repentance.

• The item's name refers to the Latin phrase "Vade Retro Satana", a phrase commonly uttered during exorcisms which roughly translates to "Stay back, Satan."
• This phrase (and its initials) are commonly engraved around crucifixes or the Saint Benedict Medal.
• The item's sprite directly represents the reverse side of said medal (which carries the phrase).
• This item's effects could be a reference to the Nuclear Throne character Melting, who has a similar activated ability.
• This is further reinforced by the fact that more powerful enemies leave larger ghosts that explode into 3 small blasts; in Nuclear Throne, larger enemies' corpses would explode in a similar fashion.
• The ability to detonate Isaac's ghost is also similar to Melting being able to use his ability one last time after death to explode his own corpse.
• The Exorcist creates red ghosts that are identical to those created by Vade Retro. These ghosts can even be blown up if Isaac has the item. Bethany Unlocks Ultra Greedier Unlocks The Binding of Isaac: Rebirth
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