Mega Satan

Mega Satan is a boss that appears in Chapter 6 (Chest, Dark Room), and is the final boss of Ending 16. • Cry Baby - Defeat Mega Satan as Isaac. • Red Baby - Defeat Mega Satan as Magdalene. • Green Baby - Defeat Mega Satan as Cain. • Brown Baby - Defeat Mega Satan as Judas. • Blue Baby - Defeat Mega Satan as ???. • Lil' Baby - Defeat Mega Satan as Eve. • Rage Baby - Defeat Mega Satan as Samson. • Black Baby - Defeat Mega Satan as Azazel. • Long Baby - Defeat Mega Satan as Lazarus. • Yellow Baby - Defeat Mega Satan as Eden. • White Baby - Defeat Mega Satan as The Lost. • Big Baby - Defeat Mega Satan as Lilith. • Noose Baby - Defeat Mega Satan as Keeper. • Mort Baby - Defeat Mega Satan as Apollyon. • Bound Baby - Defeat Mega Satan as The Forgotten. • Glowing Baby - Defeat Mega Satan as Bethany. • Illusion Baby - Defeat Mega Satan as Jacob and Esau. • Mega Chest - Defeat Mega Satan as Tainted Isaac. • Queen of Hearts - Defeat Mega Satan as Tainted Magdalene. • Gold Pill - Defeat Mega Satan as Tainted Cain. • Black Sack - Defeat Mega Satan as Tainted Judas. • Charming Poop - Defeat Mega Satan as Tainted ???. • Horse Pill - Defeat Mega Satan as Tainted Eve. • Crane Game - Defeat Mega Satan as Tainted Samson. • Hell Game - Defeat Mega Satan as Tainted Azazel. • Wooden Chest - Defeat Mega Satan as Tainted Lazarus. • Wild Card - Defeat Mega Satan as Tainted Eden. • Haunted Chest - Defeat Mega Satan as Tainted Lost. • Fool's Gold - Defeat Mega Satan as Tainted Lilith. • Golden Penny - Defeat Mega Satan as Tainted Keeper. • Rotten Beggar - Defeat Mega Satan as Tainted Apollyon. • Golden Battery - Defeat Mega Satan as Tainted Forgotten. • Confessional - Defeat Mega Satan as Tainted Bethany. • Golden Trinket - Defeat Mega Satan as Tainted Jacob.

• Afterbirth added Completion Marks for defeating Mega Satan. There are no direct achievements needed for beating Mega Satan in Rebirth aside from unlocking Ending 16.
• Mega Satan does not have a health bar, making it difficult to determine how close he is to death. The other bosses that have no health bar are Mother and The Beast.
• Mega Satan is behind an invisible wall Isaac can't move past, making him immune to contact damage effects like Midas' Touch and The Virus.
• Using Chaos Card on the first phase causes Mega Satan to go into his second phase instead of instantly killing him.
• This is because the first and second phase of the fight are actually two different enemies, and are shown as such in the bestiary.
• Mega Satan's hands count toward the mob cap total in the room, and prevent Greed, Sloth, and Fallen Gabriel from spawning enemies while they are undestroyed.
• With homing tears and The Ludovico Technique, the tear will be strongly attracted by the head even when it can't be targeted, making killing other enemies very hard.
• Unlocking the Golden Gate with the golden key and then restarting the floor with Forget Me Now or an I AM ERROR room will not cause the golden key to respawn.
• Defeating Mega Satan will not revive dead co-op players if the portal to The Void appears.

• Mega Satan's battle theme is titled Hericide,[1] and is shared with regular Satan.
• Hericide means, “to kill one’s lord or master”.[2][3]
• The Mega Satan room is actually a 1×2 room with only the lower half accessible.
• Mega Satan's second phase is referred to as "Mega Satan 2" in the bestiary.
• Mega Satan's second phase has unused sprites of skeletal hands.