Boss Rush
Room
Description
The Boss Rush is an optional room that becomes available by beating Mom in Depths, Necropolis, or Dank Depths within 20 minutes, or beating her in Mausoleum or Gehenna within 25 minutes.
Waves
The Boss Rush consists of 15 waves with 2 bosses per wave. The next wave does not spawn until both bosses from the previous wave have been killed, and any lingering monsters from previous waves will not prevent the next wave from spawning. Occasionally, all the bosses fought in the Boss Rush will be their Champion variants, if they have one.
Rebirth
All 15 waves are predetermined. * Wave 1: Blighted Ovum and Gurdy Jr. * Wave 2: Carrion Queen and The Wretched * Wave 3: Peep and The Duke of Flies * Wave 4: Blastocyst and Loki * Wave 5: Steven and Gemini * Wave 6: 3x Larry Jr. and Fistula * Wave 7: C.H.A.D. and Monstro * Wave 8: Gurdy and Chub * Wave 9: Monstro II and Gish * Wave 10: Widow and Pin * Wave 11: 3x The Hollow and The Husk * Wave 12: Mask of Infamy and The Bloat * Wave 13: Pestilence and Famine * Wave 14: Death and War * Wave 15: The Fallen and Headless Horseman
Afterbirth
All 15 waves are randomized, with each wave spawning two random bosses from the list. Each boss can only appear once per Boss Rush, meaning that out of all the 50 bosses, Isaac will face 30 of them. Note that none of the chapter 4 bosses (except Blastocyst and Death) are present in the Boss Rush: * Daddy Long Legs (101.0) Furthermore, some other bosses are not present in the Boss Rush: * All Sins and Super Sins * Uriel|display=Fallen Uriel (271.1) * Gabriel|display=Fallen Gabriel (272.2) * a+ All Afterbirth † Bosses * r All Repentance Bosses
Layouts
File:Boss Rush 2.png| a File:Boss Rush 3.png| a File:Boss Rush 4.png| a File:Boss Rush 5.png| a File:Boss Rush 6.png| a+
Notes
* If Mom is beaten within 20 minutes and Isaac enters the Angel or Devil Room, he must return to the boss room before 20 minutes have passed; otherwise, the Boss Rush entrance will be closed. ** If Isaac is teleported to the Devil Room while inside the Boss Rush room (for example, using a card), exiting the Devil Room will lead him to Mom's Boss Room. * If Isaac dies during the Boss Rush, but is able to respawn, the entrance to the Boss Rush room will still be open if the timer is still under 20 minutes. If the Boss Rush entrance has closed, the room can still be re-entered by dying in the Mom boss fight room at the cost of another life. * The Boss Rush can only be retried by picking up an item off a pedestal in its room. If the item Isaac originally picked from the room was an active item and Isaac had another item to swap it for, the pedestal and item it was swapped out for will still be there. Swapping the items again will restart the fight. Alternatively, a new pedestal can be created, such as through a card, or dropping your active item via and taking its item will also restart the fight. Also, having Broken Shovel 1 in your possession will automatically start the Boss Rush if left and entered again.
Tips
* The player's playtime can be checked at any moment by pressing TAB (or long-pressing SELECT on the controller), enabling Extra HUD in the options menu, or by simply looking down to the bottom screen on the 3DS version, where it is shown on the map. * Each boss will always drop Red Heart|display=Hearts on normal difficulty, r and sometimes on hard difficulty. Dark Bum can turn red hearts from these drops into Soul Heart|nr (Black Heart|rs), providing loads of extra health. * Take out Carrion Queen quickly, as its red poops will remain for the rest of the boss rush. They can be advantageous though, as other bosses can also take damage from these poops. In particular, bouncing bosses like The Hollow and The Husk can quickly kill themselves on contact.